Is the disease prevalence of GNEM underestimated? 

ProDGNE team members from the Lochmüller lab performed a review to establish a complete list of all known pathogenic GNE Myopathy variants from both literature and variant databases reporting that global prevalence of GNEM is greater than previous predictions and considerably more widespread than previously believed.

Check this latest article with the most comprehensive list of reported pathogenic GNE variants to date.